For educational use. This tool is intended for reference and education. All care decisions require a direct clinical assessment of the patient and independent verification of doses and values by the treating team. The calculation runs locally in your browser, no patient data is sent to any server.

Dexamethasone – for peritumoral edema

A potent long-acting corticosteroid. Reduces the oedema around brain tumors and tumor-like lesions. Not effective for trauma-related or ischaemic brain oedema.

10
mg per dose
= 2.5 mL of 4 mg/mL
Clinical notes:
  • Pediatric max: typically 16 mg/day divided (some protocols allow more).
  • If used > 7 days, taper to avoid adrenal suppression.
  • Give with a gastric protectant (e.g., omeprazole).
  • Monitor glucose daily – rises significantly.
  • Not indicated in TBI (CRASH 2004 – harm).

Reference: Roth P, et al. Corticosteroid use in neuro-oncology: an update. Neurooncol Pract 2015;2(1):6–12. PMID 26034636 · doi:10.1093/nop/npu029